Imrul Hossain, Nirmal Mazumder Tomohiro Kaino, Makoto Kawamukai, Hemanth Noothalapati, Tatsuyuki Yamamoto. Direct visualization of structurally similar polysaccharides in single yeast cells in vivo by multivariate analysis assisted Raman microspectoroscopy. J. Physical Chemistry, 127:5249-5256 (2023)

Ikuhisa Nishida, Yuki Ohmori, Ryota Yanai, Shogo Nishihara, Yasuhiro Matsuo, Tomohiro Kaino, Dai Hirata, Makoto Kawamukai. Identification of novel coenzyme Q10 biosynthetic proteins Coq11 and Coq12 in Schizosaccharomyces pombe. J Biol Chem,299:104797 (2023)

Kouhei Takenaka, Shiho Nishioka, Yuki Nishida, Makoto Kawamukai, Yasuhiro Matsuo. Tfs1, transcription elongation factor TFIIS, has an impact on chromosomal segregation affected by pka1 deletion in Schizosaccharomyces pombe. Current Genetics, 69:115-125 (2023)

Yasuhiro Matsuo, Stevan Marcus Makoto Kawamukai. Synergistic roles of the phopholipase B homolog Plb1 and the cAMP-dependent protein kinase Pka1 in the hypertonic stress response of Schizosaccharomyces pombe. Current Genetics 68:661-674 2022

Melissa A. Sleda, Zhu-Hong Li, Ranjan Behera, Baihetiya Baierna, Catherine Li, Jomkwan Jumpathong, Satish R. Malwal, Makoto Kawamukai, Eric Oldfield, VSilvia N. J. Moreno. Toxoplasma gondii Coq1 is a heptaprenyl diphosphate synthase and its inhibition by a lipophilic bisphosphonate protects mice against T. gondii infection. mBIO 13(5) e0196622 (2022)

Yuka Kawase, Takuma Tanabe, Makoto Kawamukai, Masa-aki Yoshida. Whole-genome sequencing of Psudoalteromonas. sp. strain KAN5, an agar-degrading bacterium isolated from the gut of an alga-eating fish. Microbiology resource announcement.11(8)e0039822 (2022)

Masa-aki Yoshida Takuma Tanabe Hideo Akiyoshi Makoto Kawamukai Gut microbiota analysis of Blenniidae fishes including an algae-eating fish and clear boundary formation among isolated Vibrio strains. Scientific Reports 12(1):4642 (2022)

Shin-ichi Inamura, Takuma Tanabe Makoto Kawamukai Yasuhiro Matsuo, Expression of Mug14 is regulated by the transcription factor Rst2 through the cAMP-dependent protein kinase pathway in Schizosaccharomyces pombe. Gurrent Genetics 67(5):807-821(2021)

Keisuke Tomita, Yoko Yashiroda, Yasuhiro Matsuo, Jeff Piotrowski, Sheena Li, Reika Okamoto, Mami Yoshimura, Hiromi Kimura, Yumi Kawamura, Makoto Kawamukai,Charles Boone, Minoru Yoshida, Hideaki Nojiri, Kazunori Okada. Genome-wide screening of genes associated with Momilactone B sensitivity in the fission yeast Schizosaccharomyces pombe. G3 11(8):jkab156 (2021)


Ikuhisa Nishida, Ryota Yanai, Yasuhiro Matsuo, Tomohiro Kaino, Makoto Kawamukai,Benzoic acid inhibits Coenzyme Q biosynthesis in Schizosaccharomyces pombe PLoS One.15(11):e0242616. (2020)

Takuma Tanabe, Makoto Kawamukai, Yasuhiro Matsuo. Glucose limitation and pka1 deletion rescue aberrant mitotic spindle formation induced by Mal3 overexpression in Schizosaccharomyces pombe. Biosci Biotechnol Biochem. 84(8):1667-1680.(2020)

Nungnit Wattanavichean, Ikuhisa Nishida, Masahiro Ando, Makoto Kawamukai, Tatsuyuki Yamamoto, Hiro-o Hamaguchi. Organelle specific simultaneous Raman/green fluorescence protein microspectroscopy for living cell physicochemical studies J. Biophotonics 13(4):e201960163 (2020)

Ikuhisa Nishida, Kazumasa Yokomi, Kouji Hosono, Kazuhiro Hayashi, Yauhiro Matsuo, Tomohiro Kaino, Makoto Kawamukai. CoQ10 production in Schizosaccharomyces pombe is increased by reduction of glucose leveles or deletion of pka1. Appl. Microbiol. Biotechnol 103：4899-4915 (2019)

Takuma Tanabe, Masayuki Yamaga, Makoto Kawamukai, Yasuhiro Matsuo. Mal3 is a multi-copy suppressor of the sensitivity to microtuble-deporimerizing drugs and chromosome mis-segregation in a fission yeast pka1 mutant. PloS One 14(4):e0214803 (2019)

Shiho Morisada, Ikuhisa Nishida, Makoto Kawamukai, Hiroyuki Horiuchi, Ryouichi Fukuda. Suppression of respiratory growth defect of mutant deficient in mitochondrial phopholipase A1 by overexpression of genes involved in coenzyme Q synthesis in Saccharomyces cerevisiae. Bioscie. Biotechnolo. Biochem. 82:1633-1639 (2018)

Tomohiro Kaino, Kai Tonoko, Shiomi Mochizuki, Yuriko Takashima, Makoto Kawamukai. Schizosaccharomyces japonicus has low levels of CoQ10 synthesis, respiration deficiency, and efficient ethanol production at high temperature. Biosci. Biotechnol. Biochem. 82:1031-1042 (2018)

Makoto Kawamukai. Biosyntheisis and applications of prenylquinones Biosci. Biotechnol. Biochem. 82:963-977 (2018)

Hemanth Noothalapati, Ryo Ikarashi, Keita Iwasaki, Tatsuro Nishida, Tomohiro Kaino, Keisuke Yoshikiyo, Keiji Terao,  Daisuke Nakata, Naoko Ikuta,, Masahiro Ando, Hiro-o Hamaguchi, Makoto Kawamukai, Tatsuyuki Yamamoto. Studying anti-oxidative properties of inclusion complexes of alfa-lipoic acid with gamma-cyclodextrin in single living fission yeast by confocal Raman microspectroscopy. Spectrochimica Acta A Mol Biomol Spectrosc. 197:237-243 (2018)

Kouhei Takenaka, Takuma Tanabe, Makoto Kawamukai, Ysuhiro Matsuo, Overexpression of the transcription factor Rst2 in Schizosaccharomyces pombe indicates growth defect, mitotic defects, and microtubule disorder. Biosci. Biotechnol. Biochem. 82:247-257(2018)


Tomohiro Kaino, Kai Tonoko, Shiomi Mochizuki, Yuriko Takashima, Makoto Kawamukai. Schizosaccharomyces japonicus has low levels of CoQ10 synthesis, respiration deficiency, and efficient ethanol production at high temperature. Biosci. Biotechnol. Biochem. (in press)

Tomohiro Yamaki, Masahiro Otani, Kohei Ono, Takuro Mimura, Koshiro Oda, Takeshi Minamii, Shingo Matsumoto, Yuzy Matsuo, Makoto Kawamukai, Takashi Akihiro. Isolation and characterization of rice cesium tansporter genes from a rice-transporter-enrihced yeast expression library. Physiologia Plantarum 160:425-436 (2017)

Kohei Nishino, Misaki Kushima, Tomohiro Kaino, Yasuhiro Matsuo, Makoto Kawamukai. Urea enhances cell lysis of Schizosaccharomyces pombe ura4 mutants. Biosci. Biotechnol. Biochem 81:1444-1451(2017)

Sean Qiu Lee, Tsu So Tan, Makoto Kawamukai Ee Sin Chen.  Cellular Factories for CoenzymQ10 production. Microbial Cell Factories 16(1):39 (2017)

Yorinaga Y, Kumasaka T, Yamamoto M, Hamada K, Kawamukai M. Crystal structure of a family 80 chitosanase from Mitsuaria chitosanitabida. FEBS Lett. doi: 10.1002/1873-3468.12557. 2017

Daisuke Moriyama, Tomohiro Kaino, Kazuyoshi Yajima, Ryota Yanai, Yasuhiro Ikenaka, Junzo Hasegawa, Motohisa Washida, Hirokazu Nanba, Makoto Kawamukai. Cloning and characterization of decaprenyl dihosphate synthase from three different fungi. Appl. Microbiol. Biotechnol. 101(4):1559-1571(2017)

Murai M, Matsunobu K, Kudo S, Ifuku K, Kawamukai M, Miyoshi H. Identification of the Binding Site of the Quinone-Head Group in Mitochondrial Coq10 by Photoaffinity Labeling. Biochemistry 53:3359-4003 (2014)

Kazuhiro Hayashi, Yuki Ogiyama, Kazumasa Yokomi, Tsuyoshi Nakagawa, Tomohiro Kaino, Makoto Kawamukai. Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. PLoS ONE 9(6)e99038 (2014)

Hiroaki Kato, Shintaro Kira and Makoto Kawamukai. The transcription factors Atf and Pcr1 are essential for transcriptional induction of the extracellular maltase Agl1 in fission yeast. PLoS ONE 8(3)e80572 (2013)

Yuji Tanaka, Kohji Nishimura, Makoto Kawamukai, Akinobu Oshima, Tsuyoshi Nakagawa. Redundant function of two Arabidopsis COPII components, AtSec24B and AtSec24C, are essential for male and femal gametogenesis. Planta 238:561-575 (2013)

Tatsuro Nishida, Tomohiro Kaino, Ryo Ikarashi, Daisuke Nakata, Keiji Terao, Masahiro Ando, Hiroo Hamaguchi, Makoto Kawamukai, Tatsuyuki Yamamoto. The effect of coenzyme Q10 included by gamma-cyclodextrin on the growth of fission yeast studied by microscope Raman spectroscopy. J. Molecular Structure  375-381(2013)

Yuzy Matsuo, Kouhei Nishino, Kouhei Mizuno, Takashi Akihiro, Takashi Toda, Yasuhiro Matsuo, Tomohiro Kaino and Makoto Kawamukai. Polypeptone induces dramatic cell lysis in ura4 deletion mutants in fission yeast PLoS ONE 8(3):e59887(2013)

Tomohiko Matsuzawa, Youko Kageyama, Kazuyoshi Ooishi, Makoto Kawamukai, and Kaoru Takegawa. The Zinc finger protein Gsf1 regulates Gsf2-dependent flocculation in fission yeast. FEMS Yeast Research 13:259-266 (2013)

Katsuhiro Tanae, Tomitaka Horiuchi, Takuya Yamakawa, Yuzy Matsuo, and Makoto Kawamukai. Sim3 shares some common roles with the histone chaperone Asf1 in fission yeast. FEBS Lett 586:4190-4196(2012)

Kaino T, Tasaka Y, Tatehashi Y, Takagi H. Functional Analysis of the C-Terminal Region of γ-Glutamyl Kinase of Saccharomyces cerevisiae.
Biosci Biotechnol Biochem. 76(3):454-61 (2012).

Shinya Nakamura, Takamasa Suzuki, Makoto Kawamukai, Tsuyoshi Nakagawa. Expression analysis of Arabidopsis thaliana small secreted protein genes. Biosci. Biotechnol. Biochem 76:434-436 (2012)

Katsuhiro Tanae, Tomitaka Horiuchi, Yuzy Matsuo, Satoshi Katayama, Makoto Kawamaukai. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. PLoS ONE　7:e30472 (2012)

Mi-Suk Seo, Sakiko Takahashi, Koh-ichi Kadowaki, Makoto Kawamukai, Manabu Takahara, Tadashi Takamizo. Expression of CoQ10-producing ddsA transgene by efficient Agrobacterium-mediated transformaion in Panicum meyerianum. Plant Cell Tiss Organ Cult 107:325-332(2011)

Tanaka Y, Nakamura S, Kawamukai M, Koizumi N, Nakagawa T.Development of a Series of Gateway Binary Vectors Possessing a Tunicamycin Resistance Gene as a Marker for the Transformation of Arabidopsis thaliana. Biosci Biotechnol Biochem. 75:804-807 (2011)

Yasuo Oowatari, Heetae Jeong, Katsuhiro Tanae, Tsuyoshi Nakagawa. Makoto Kawamukai. Regulation and role of an RNA-binding protein Msa2 in controlling the sexual differentiation in fission yeast. Current Genetics 57:191-200 (2011).

Yuzy Matsuo, Hayafumi Kishimoto, Katsuhiro Tanae, Kenji Kitamura, Satoshi Katayama, Makoto Kawamukai. Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast. J. Biol. Chem　286:13775-13790 (2011).

Nobuhiko Mukai, Kazuo Masaki Tsutomu Fujii, Makoto Kawamukai, Haruyuki Iefuji. PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae. J. Biosci. Bioengin. 109:564-569 (2010).
Yuzy Matsuo, Hayafumi Kishimoto, Tomitaka Horiuchi, Katsuhiro Tanae, Makoto Kawamukai. Simple and effective gap-repair cloning using short tracts of flanking homology in fission yeast. Biosci. Biotechnol. Biochem. 74:685-689 (2010)

Tie-Zhong Cui, Tomohiro Kaino, Makoto Kawamukai. A subunit of decaprenyl diphosphate synthase stabilizes octaprenyl diphosphate synthase in Escherichia coli by forming a high-molecular weight complex. FEBS Lett 584, 652-656 (2010)

Sakiko Takahashi, Toshikazu Ohtani, Hikaru Satoh, Yasunori Nakamura, Makoto Kawamukai, Koh-Ichi Kadowaki. Development of Coenzyme Q10-enriched rice using sugary and shrunken mutants. Biosci. Biotechnol. Biochem. 74, 182-184 (2010)

Nakamura S, Nakao A, Kawamukai M, Kimura T, Ishiguro S, Nakagawa T. Development of Gateway binary vectors, R4L1pGWBs, for promoter analysis in higher plants.Biosci Biotechnol Biochem. 73(11):2556-2559 (2009)

Sakiko Takahashi, Toshikazu Ohtani, Shuichi Iida, Yoshihiro Sunohara, Kei Matsushita, Hideo Maeda, Yoshitaka Tanetani, Kiyoshi Kawai, Makoto Kawamukai, Koh-Ichi Kadowaki. Development of CoQ10-riched rice from giant embryo lines. Breeding Science 59:321-326 (2009)

Swapan Kumar Paul, Yasuo Oowatari Makoto Kawamukai. A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast . FEBS J 276:5076-5093 (2009)

Yasuo Oowatari, Kenichi Toma, Fumiyo Ozoe, Makoto Kawamukai. Identification of sam4 as a rad24 allele in Schizosaccharomyces pombe. Biosci. Biotechnol. Biochem. 73:1591-1598 (2009)

Swapan Kumar Paul, Md. Muniruzzaman Goldar, Miyo Yakura, Yasuo Oowatari, Makoto Kawamukai. Glutamyl tRNA synthetases and glutamic acid induce sexual differentiation of Schizosaccharomyces pombe. Biosci. Biotechnol. Biochem. 73:1339-1347 (2009)

Makoto Kawamukai. Biosynthesis and bioproduction of coenzyme Q10 by yeasts and other organisms. Biotechnol. Appl. Biochem. 53:217-226 (2009)

Tie-Zhong Cui, Makoto Kawamukai. Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyce pombe FEBS J. 276:748-759 (2009)

Mei Zhang, Shusoh Wakitani, Kazuhiro Hayashi, Risa Miki, Makoto Kawamukai. High production of sulfide in coenzyme Q deficient fission yeast Biofactors 32, 91-98 (2008)

Risa Miki, Ryoichi Saiki, Yoshihisa Ozoe, Makoto Kawamukai. Comparison of a coq7 deletion mutant with other respiration-defective mutants in fission yeast. FEBS J. 275:5309-5324(2008)

Ryoichi Saiki, Adam L. Lunceford, Yuchen Shi, Beth Marbois, Rhonda King, Justin Pachuski, Makoto Kawamukai, David L. Gasser, and Catherine F Clarke, Coenzyme Q10 supplementation rescues renal disease in Pdss2 kd/kd mice with mutations in prenyl diphosphate synthase subunit2. Am J Physiol Renal Physiol. 295 F1534-1544 (2008)

Mei Zhang, Jun Luo, Yuki Ogiyama, Ryoichi Saiki, Makoto Kawamukai. Heteromer formation of a long-chain prenyl diphosphate synthase from fission yeast Dps1 and budding yeast Coq1. FEBS J. 275:3653-3668 (2008)

Takumi Suizu, Guo-Lei Zhou, Yasuo Oowatari and Makoto Kawamukai. Analysis of expressed sequence tags (ESTs) from Lentinula edodes. Appl. Microbiol. Biotechnol. (2008)

Nakagawa T, Nakatsuka A, Yano K, Yasugahira S, Nakamura R, Sun N, Itai A, Suzuki T, Itamura H. Expressed sequence tags from persimmon at different developmental stages. Plant Cell Rep. (2008)

Hamamoto S, Marui J, Matsuoka K, Higashi K, Igarashi K, Nakagawa T, Kuroda T, Mori Y, Murata Y, Nakanishi Y, Maeshima M, Yabe I, Uozumi. Characterization of a tobacco TPK-type K+ channel as a novel tonoplast K+ channel using yeast tonoplasts.J Biol Chem. 283(4):1911-20. (2008)

Tsuyoshi Nakagawa, Shinya Nakamura, Katsunori Tanaka, Makoto Kawamukai,Takamasa Suzuki, Kenzo Nakamura, Tetsuya Kimura, Sumie Ishiguro, Develpoment of R4 gateway binary vectors (R4pGWB) enabling high-throughput promoter swapping for plant research. Biosci Biotechnol Biochem 72;624-629 (2008)

Yanfang Ye, Makoto Fujii, Aiko Hirata, Makoto Kawamukai. Chikashi Shimoda, Taro Nakamura. Geranylgeranyl diphosphate synthase in fission yeast is a heteromer of farnesyl diphosphate synthase (FSP), Fps1 and FPS-like protein , Spo9, essential fo sporulation. Mol. Biol. Cell 18,3568-3581(2007)

Tsuyoshi Nakagawa, Takayuki Kurose, Takeshi Hino, Katsunori Tanaka, Makoto Kawamukai, Yasuo Niwa, Kiminori Toyooka, Ken Matsuoka, Tetsuro Jinbo, Tetsuya Kimura. Development of series of gateway binary vectors, pGWBs, for realizing efficient construction of fusion genes for plant transformation. J. Biosci. Bioengin. 104:34-41(2006).

Hitoshi KAWAMOTO, Yasunari MIKI, Takayuki KIMURA, Katsunori TANAKA, Tsuyoshi NAKAGAWA, Makoto KAWAMUKAI, Hideyuki MATSUDA. Effects of fucoidan from Mozuku on human stomach cell lines. Food Sci. Technol. Res. 12(3),218-222 (2006)

Ferella M, Montalvetti A, Rohloff P, Miranda K, Fang J, Reina S, Kawamukai M, Bua J, Nilsson D, Pravia C, Katzin A, Cassera MB, Aslund L, Andersson B, Docampo R, Bontempi EJ.   A solanesyl diphosphate synthase localizes in glycosomes of Trypanosoma cruzi. J Biol Chem. 281,39339-39348 (2006)

Mamnun YM, Katayama S, Toda T.  Fission yeast Mcl1 interacts with SCF(Pof3) and is required for centromere formation. Biochem Biophys Res Commun. 350:125-130 (2006)

Matsuo Y, Asakawa K, Toda T, Katayama S.  A rapid method for protein extraction from fission yeast.  Biosci Biotechnol Biochem.  70(8):1992-1994 (2006)

Hitoshi KAWAMOTO, Akio HORIBE, Yasunari MIKI, Takayuki KIMURA, Katsunori TANAKA, Tsuyoshi NAKAGAWA, Makoto KAWAMUKAI, Hideyuki MATSUDA. Cloning and Sequencing Analysis of Alginate Lyase Genes from Marine Bacterium Vibrio sp. O2. Marine Biotechnology (2006)

Miyo Yakura, Yasue Ishikura, Yoshimi Adachi, Makoto Kawamukai, Involvement of Moc1 in sexual development and survival of Schizosaccharomyces pombe. Biosci. Biotechnol. Biochem. 70:1740-1749 (2006)

Choong Soo Yun, Hideyuki Matsuda, Makoto Kawamukai. Directed evolution to enhance secretion efficiency and thermostability of chitosanase from Mitsuaria chitosanitabida 3001 Biosci. Biotechnol. Biochem. 70:559-563 (2006)

Sakiko Takahashi, Yuki Ogiyama, Hiroaki Kusano, Hiroaki Shimada, Makoto Kawamukai, Koh-ichi Kadowaki. Metabolic engineering of Coenzyme Q by modification of isoprenoid side chain in plant. FEBS Lett. 580:955-959 (2006)

Miyo Yakura, Fumiyo Ozoe, Hideki Ishida, Tsuyoshi Nakagawa, Katsunori Tanaka, Hideyuki Matsuda, and Makoto Kawamukai.zds1, a novel gene encoding an ortholog of Zds1 and Zds2, controls sexual differentiation, cell wall integrity, and cell morphology in fission yeast. Genetics 172:811-825 (2006)

Md Muniruzzaman Goldar, Hee tae Jeong, Katsunori Tanaka, Hideyuki Matsuda, and Makoto Kawamukai. Moc3, a novel Zn finger type protein involoved in sexual development, ascus formation, and stress response of Schizosaccharomyces pombe. Curr. Genet. 48:345-355 (2005)

Ryoichi Saiki, Ai Nagata,Tomohiro Kainou, Hideyuki Matsuda, and Makoto Kawamukai.Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans. FEBS J. 56:5606-5622 (2005)

ChoongSoo YUN, Daiki AMAKATA, Yasuhiro MATSUO, Hideyuki MATSUDA, and Makoto KAWAMUKAI. New chitosan-degrading strains that produce chitosanases similar to ChoA of Mitsuaria chitosanitabida. Appl. Environ. Microbiol. 71:5138-5144 (2005)

Daiki Amakata, Yasuhiro Matsuo, Kumiko Shimono, Jae Kweon Park, Choong Soo Yun, Hideyuki Matsuda, Akira Yokota and Makoto Kawamukai. Mitsuaria chitosanitabida gen. nov., sp. nov., an aerobic, chitosanase-producing member of the 'Betaproteobacteria' IJSEM,55:1927-1932 (2005)

Md. Muniruzzaman Goldar, Toshikazu Nishie, Yasue Ishikura, Toshifumi Fukuda, Kaoru Takegawa, and Makoto Kawamukai, Functional conservation between fission yeast moc1/sds23 and its two orthologs, budding yeast SDS23 and SDS24, and phenotypic differences in their disruptants. Biosci. Biotechnol, Biochem. 69(7):1422-1426 (2005)

Yasuhiro Matsuo, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai. cda1+, encoding chitin deacetylase is required for proper spore formation in Schizosaccharomyces pombe. FEBS Lett. 579, 2737-2743 (2005)

Park YC, Kim SJ, Choi JH, Lee WH, Park KM, Kawamukai M, Ryu YW, Seo JH.Batch and fed-batch production of coenzyme Q(10) in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans.Appl Microbiol Biotechnol. 67, 192-196 (2005)

Luo Jun,Ryoichi Saiki, Kei Kawamura, Tsuyoshi Nakagawa, and Makoto Kawamukai. Identification and subcellular localization of two solanesyl diphosphate synthases from Arabidopsis thaliana.Plant Cell Physiol. 45:1882-1888.(2004)

Surang Engprasert, Futoshi Taura, Makoto Kawamukai, Yukihiro Shoyama, Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq. BMC Plant Biol. on line (2004)

Kazunori Okada, Kazuaki Ohara, Kazufumi Yazaki, Kouhei Nozaki, Naonori Uchida, Makoto Kawamukai, Hideaki Nojiri and Hisakazu Yamane, The AtPPT1 gene encoding 4-hydroxybenzoate polyprenyl diphosphate transferase in ubiquinone biosynthesis is required for embryo development in Arabidopsis thaliana.Plant Mol. Biol.55:567-577 (2004)

Yasuhiro Matsuo, Yoshinori Matsuura, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai. Chr4, a Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae Chs4p/Skt5p protein, is related to septum formation and is required for the proper localization of Chs2. Yeast 21:1005-1019 (2004)

Takaharu Yamamoto, Yuji Chikashige, Fumiyo Ozoe, Makoto Kawamukai, and Yasushi Hiraoka. Activation of the pheromone-responsive MAP kinase drives haploid cells to ectopic meiosis with normal telomere clustering and sister chromatid segregation in fission yeast. J. Cell. Sci. 11:3875-3886 (2004)

Hee Tae Jeong, Yasuo Oowatari, Michiyo Abe,  Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai. Interaction between a negative regulator (Msa2/Nrd1)  and a positive regulator (Cpc2) of sexual differentiation in Schizosaccharomyces pombe. Biosci. Biotech. Biochem 68:1621-1626 (2004)

Yasuhiro Matsuo, Katsunori Tanaka, Tsuyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. Genetic analysis of chs1+ and chs2+ encoding chitin synthase from Schizosaccharomyces pombe. Biosci. Biotech. Biochem. 68:1489-1499 (2004)

Tanaka K, Russell P.Cds1 Phosphorylation by Rad3-Rad26 Kinase Is Mediated by Forkhead-associated Domain Interaction with Mrc1.J. Biol. Chem. 279(31):32079-32086 (2004)

Hee Tae Jeong, Fumiyo Ozoe,  Katsunori Tanaka, Tusyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe. Genetics 167: 77-91 (2004)

Kaori Tanabe, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai.Truncated Sla1 induces haploid meiosis through the Pat1-Mei2 system in fission yeast. Biosci. Biotech. Biochem.68：226-270 (2004)

Kaori Tanabe, Noriko Ito, Tomomi Wakuri, Fumiyo Ozoe, Makoto Umeda, Satoshi Katayama, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai. Sla1, a Schizosaccharomyces pombe homolog of the human La protein, induces ectopic meiosis when its C-terminus is truncated. Eukaryotic Cell 2:1274-1287 (2003)

Ryoichi Saiki, Yuki Ogiyama, Tomohiro Kainou, Tomoko Nishi, Hideyuki Matsuda, and Makoto Kawamukai. Pleiotropic phenotypes of fission yeast defective in ubiquinone-10 production. A study from the abc1Sp (coq8Sp) mutant. Biofactors 18:229-235 (2003)

Hui Zhao, Katunori Tanaka, Eishi Nogochi, Chiaki Nogochi, Paul Russell. Replication checkpoint protein Mrc1 is regulated by Rad3 and Tel1 in fission yeast. Mol. Cell. Biol.23, 8395-8403 (2003)

Ryoichi Saiki, Ai Nagata, Naonori Uchida, Tomohiro Kainou, Hideyuki Matsuda, and Makoto Kawamukai. Fission yeast decaprenyl diphosphate synthase consists of Dps1 and the newly characterized Dlp1 protein in a novel heterotetrameric structure. Eur. J. Biochem. 270：4113-4121 (2003)

Makoto Kawamukai. Biosynthesis, bioproduction and novel roles of ubiquinone. J. Biosci. Bioeng. 94, 511-517(2002)

Fumiyo Ozoe, Rumi Kurokawa, Yasuyo Kobayashi, Hee Tae Jeong, Katsunori Tanaka, Kikuo Sen, Tsuyoshi Nakagawa, Hideyuki Matsuda, Makoto Kawamukai. The 14-3-3 proteins Rad24 and Rad25 negatively regulate Byr2 by affecting its localization in Schizosaccharomyces pombe. Mol. Cell. Biol 22:7105-7119 (2002)

Nakagawa H, Lee JK, Hurwitz J, Allshire RC, Nakayama J, Grewal SI, Tanaka K, Murakami Y.  Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications. Genes Dev.  16, 1766-1778 (2002)

Kumiko Shimono, Hideyuki Matsuda, and Makoto Kawamukai. Functional expression of chitinase and chitosanase, and their effects on morhphologies in the yeast Schizosaccharomyces pombe. Biosci. Biotech. Biochem. 66(5);1143-1147 (2002)

Kumiko Shimono, Kazutaka Shigeru, Akiho Tsuchiya, Noriko Itou, Yukari Ohta, Katsunori Tanaka, Tsuyoshi Nakagawa, Hideyuki Matsuda, and Makoto Kawamukai. Two glutamic acids in chitosanase A from Matsuebacter chitosanotabidus 3001 are the catalytically important residues. J. Biochem. 131:87-96 (2002)

Tanaka, K. & Russell, P. Mrc1 channels DNA replication arrest signal to checkpoin kinase Cds1 Nature Cell Biol. 3:966-972 (2001)

Lopez-Girona A, Tanaka K, Chen XB, Baber BA, McGowan CH, Russell P. Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast. Proc Natl Acad Sci U S A. 98(20):11289-94. (2001)

Katsunori Tanaka, Michael, N. Boddy, Xiao-Bo Chen, Clare H. McGowan, and Paul Russell, Threonine-11, phosphorylated by Rad3 and ATM in vitro, is required for activation of fission yeast checkpoint kinase Cds1. Mol. Cell Biol.  15:3398-3404 (2001)

Tomohiro Kainou, Kazunori Okada, Kengo Suzuki, Tsuyoshi Nakagwa, Hideyuki Matsuda and Makoto Kawamukai. Dimer formation of octaprenyl diphosphate synthase (IspB) is essential for chain length determination of ubiquinone. J. Biol. Chem. 276 (11), 7876-7883, (2001)

Kazuhiko Takeda, Chiyuri Akimoto, Makoto Kawamukai. Effects of the Escherichia coli sfsA gne on mal genes expression and a DNA binding activity of SfsA. Biosci. Biotech. Biochem. 65:213-217  (2001)

Naonori Uchida, Kengo Suzuki, Ryoichi Saiki, Tomohiro Kainou, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai.  Phenotypes of fission yeast defective in ubiquinone production due to disruption of the gene for p-hydroxybenzoate polyprenyl diphosphate tranferase. J. Bacteriol. 182: 6933-6939 (2000)

Kazunori Okada, Takeshi Saito, Tsuyoshi Nakagwa, Makoto Kawamukai and Yuji Kamiya. Five geranylgeranyl diphosphate synthases expressed in different organs are localized into three subcellular compartments in Arabidopsis. Plant Physiol. 122:1045-1056 (2000)

Guo - Lei Zhou, Takaharu Yamamoto, Fumiyo Ozoe, Daisuke Yano, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai. Identification of a 14-3-3 protein from Lentinus edodes that interacts with CAP (adenylyl cyclase - associated protein), and conservation of this interaction in fission yeast.Biosci. Biotech. Biochem. 64:149-159　(2000)

Katsunori Tanaka, Junko Nishide, Koei Okazaki, Hiroaki Kato, Osami Niwa, Tsuyoshi Nakagawa, Hideyuki Matsuda, Makoto Kawamukai and Yota Murakami. Characterization of a fission yeast SUMO-1 homologue, Pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation.　Mol. Cell Biol.19:8660-8672 (1999)

Jae Kweon Park, Kumiko Shimono, Nobuhisa Ochiai, Kazutaka Shigeru, Masako Kurita, Yukari Ohta, Katsunori Tanaka, Hideyuki Matsuda, and Makoto Kawamukai. Purification, characterization, and gene analysis of a chitosanase (ChoA) from Matsuebacter chitosanotabidus 3001. J. Bacteriol. 181:6642-6649 (1999)

Yasuhiro Matsuo, Masako Kurita, Jae Kweon Park, Katsunori Tanaka, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Purification, characterization and gene analysis of N-acetylglucosaminidase from Enterobacter sp. G-1. Biosci. Biotech. Biochem. 63:1261-1268 (1999)

Tomohiro Kainou, Kei Kawamura, Katsunori Tanaka, Hideyuki Matsuda and Makoto Kawamukai. Identification of the GGPS1 genes encoding geranylgeranyl diphosphate synthases from mouse and human. Biochim. Biophys.Acta. 1437:333-340 (1999)

Makoto Kawamukai. Isolation of a novel gene, moc2, encoding a putative RNA helicase as a suppressor of sterile strains in S. pombe. Biochim. Biophys.Acta. 144:1173-1186. (1999)

Takeshi Saito, Kei Tadakuma, Naoko Takahashi, Hiroyuki Ashida, Katsunori Tanaka, Makoto Kawamukai, Hideyuki Matsuda and Tsuyoshi Nakagawa. Two cytosolic cyclophilin genes of Arabidopsis thaliana differently regulated in temporal- and organ-specific expression. Biosci. Biotech. Biochem. 63:632-637 (1999)

Takeshi Saito, Yasuo Niwa, Hiroyuki Ashida, Katsunori Tanaka, Makoto Kawamukai, Hideyuki Matsuda and Tsuyoshi Nakagawa. Expression of a gene for cyclophilin which contains an amino-terminal endoplasmic reticulum-targeting signal. Plant Cell Physiol. 40 (1) 77-87 (1999)

Guo-Lei Zhou, Yasumasa Miyazaki, Tsuyoshi Nakagawa, Katsunori Tanaka, Kazuo Shishido, Hideyuki Matsuda and Makoto Kawamukai.Identification of a CAP (adenylyl-cyclase-associated protein) homologous gene in Lentinus edodes and its functional complementation of yeast CAP mutants. Microbiology 144:1085-1093 (1998)

Kazunori Okada, Tomohiro Kainou, Hideyuki Matsuda and Makoto Kawamukai. Biological significance of the side chain length of ubiquinone in Saccharomyces cerevisiae. FEBS lett. 431:241-244 (1998)

Kazunori Okada, Tomohiro Kainou, Katsunori Tanaka, Tsuyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. Molecular cloning and mutational analysis of the ddsA gene encoding decaprenyl diphosphate synthase from Gluconobacter suboxydans. Eur. J. Biochem. 255(1): 52-59 (1998)

Jae Kweon Park, Takashi Okamoto, Yukikazu Yamasaki, Katsunori Tanaka, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Molecular cloning, nucleotide sequencing, and regulation of the chiA gene encoding one of chitinases from Enterobacer sp. G-1. J. Ferment Bioeng. 84:493-501 (1997)

Jae Kweon Park, Kenji Morita, Ikuo Fukumoto, Yukikazu Yamasaki, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Purification and characterization of the chitinase (ChiA) from Enterobacter sp. G-1. Biosci. Biotech. Biochem. 61:684-689 (1997)

Kazunori Okada, Yasuhiro Kamiya, XuFen Zhu, Kengo Suzuki, Katsunori Tanaka, Tsuyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. Cloning of the sdsA gene encoding solanesyl diphosphate synthase from Rhodobacter capsulatus and its functional expression in Escherichia coli and Saccharomyces cerevisiae. J. Bacteriol. 179:5992-5998 (1997)

Kazunori Okada, Masaru Minehira, XuFen Zhu, Kengo Suzuki, Tsuyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. The ispB gene encoding octaprenyl diphosphate synthase is essential for growth of Escherichia coli. J. Bacteriol 179:3058-3060 (1997)

XuFen Zhu, Kengo Suzuki, Takeshi Saito, Kazunori Okada, Katsunori Tanaka, Tsuyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. Geranyl geranyl pyrophosphate synthase encoded by the newly isolated gene GGPS6 from Arabidopsis thaliana is localized in mitochondria. Plant Mol Biol. 35:331-341 (1997)

Kengo Suzuki, Kazunori Okada, Yasuhiro Kamiya, XuFen Zhu, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Analysis of the decaprenyl diphoshate synthase (dps) gene in fission yeast suggests a role of ubiquinone as an antioxidant. J. Biochem. 121:496-505 (1997)

XuFen Zhu, Kengo Suzuki, Kazunori Okada, Katsunori Tanaka, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Cloning and functional expression of a novel geranylgeranyl pyrophosphate synthase gene from Arabidopsis thaliana in Escherichia coli. Plant Cell Physiol. 38:357-361 (1997)

Kazunori Okada, Kengo Suzuki, Yasuhiro Kamiya, XuFen Zhu, Shingo Fujisakai, Yukinobu Nishimura, Tokuzo Nishino, Tsuyoshi Nakagawa, Makoto Kawamukai, Hideyuki Matsuda. Polyprenyl diphosphate synthase essentially defines the length of the side chain of ubiquinone. Biochim. Biophys.Acta. 1302/3:217-223 (1996)

Satoshi Katayama, Fumiyo Ozoe, Rumi Kurokawa, Katsunori Tanaka, Tsuyoshi Nakagawa, Hideyuki Matsuda and Makoto Kawamukai. Genetic analysis of the sam mutations, which induce sexual development with no requirement for nutritional starvation in fission yeast. Biosci. Biotech. Biochem. 60:994-999 (1996)

Emma L. Spence, Makoto Kawamukai, Jonathan Sanvoism, Helen Braven and Timothy D. H. Bugg. Catechol dioxygenases from Escherichia coli (MhpB) and Alcaligenes eutrophus (MpcI):Sequence analysis and biochemical properties of a third family of extradiol dioxygenases. J. Bacteriol 178:5249-5256 (1996)

Taguchi Y, Tanaka K, Honda Y, Miao DM, Sakai H, Komano T, Bagdasarian M. A dnaA box can functionally substitute for the priming signals in the oriV of the broad host-range plasmid RSF1010. FEBS Lett Jun 17;388(2-3):169-72 （1996）

Miao DM, Sakai H, Okamoto S, Tanaka K, Okuda M, Honda Y, Komano T, Bagdasarian M. The interaction of RepC initiator with iterons in the replication of the broad host-range plasmid RSF1010. Nucleic Acids Res Aug 25;23(16):3295-300 （1995）

Miao DM, Sakai H, Tanaka K, Honda Y, Komano T, Bagdasarian M. Functional distinction among structural subsections in the specific priming signal for DNA replication of the broad host-range plasmid RSF1010. Biosci Biotechnol Biochem May;59(5):920-1 （1995）

Ryutaro Utsumi, Takahiro Nakayama, Naomi Iwamoto, Kumiko Kohda, Makoto Kawamukai, Hiroyuki Tanabe, Kan Tanaka, Hideo Takahashi and Manjiro Noda. Mutational analysis of the fic promoter recognized by RpoS (σ３８) in 　 Escherichia coli. Biosci. Biotech. Biochem. 59:1573-1575. (1995).

Soo-Yeol Chung, Yong-Lark Choi, Moo-Je Cho, Hajime Yoshisue, Makoto Kawamukai, Hiroshi Sakai and Tohru Komano. Transcription of sfs4, one of the genetic elements related to CRP*-dependent expression of Escherichia coli mal genes. J. Gen. Appl. Microbiol. 41:257-262. (1995).

XuFen Zhu, Mihoko Yuasa, Kazunori Okada, Kengo Suzuki, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Production of ubiquinone in Escherichia coli by expression of various genes responsible for ubiquinone biosynthesis. J. Ferment. Bioeng. 79(5):493-495. (1995).

Satoshi Katayama, Nami Adachi, Kota Takao, Tsuyoshi Nakagawa, Hideyuki Matsuda, and Makoto Kawamukai. Molecular cloning and sequencing of the hcs gene, which encodes 3-hydroxy-3-methylglutaryl coenzyme A synthase of Schizosaccharomyces pombe. Yeast 11：1533-1537. (1995)

Takeshi Saito, Sumie Ishiguro, Hiroyuki Ashida, Makoto Kawamukai, Hideyuki Matsuda, Hideo Ochiai and Tsuyoshi Nakagawa. Cloning and sequence analysis of genes for cyclophilin from Arabidopsis thaliana. Plant Cell Physiol. 36(2): 377-382 (1995).

Kengo Suzuki, Minoru Ueda, Mihoko Yuasa, Tsuyoshi Nakagawa, Makoto Kawamukai, and Hideyuki Matsuda. Evidence that E. coli ubiA product is a functional homolog of yeast COQ2 and the regulation of the ubiA gene expression. Biosci. Biotech. Biochem. 58(10), 1814-1819. (1994).

Ken-ichi Asai, Shingo Fujisaki, Yukinobu Nishimura, Tokuzo Nishino, Kazunori Okada, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. The identification of Escherichia coli ispB (cel) gene encoding the octaprenyl diphosphate synthase. Biochem. Biophys. Res. Commun. 202:340-345. (1994).

Yukikazu Yamasaki, Yukari Ohta, Jae Gweon Park, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Induction of the enzymes that degrade chitin and chitosan from Enterobacter sp. G-1. Bull. Fac. Agr. Shimane Univ. 28:107-117 (1994).

Yukikazu Yamasaki, Isami Hayashi, Yukari Ohta, Tsuyoshi Nakagawa, Makoto Kawamukai, and Hideyuki Matsuda. Purification and mode of action of chitosanolytic enzyme from Enterobacter sp. G-1. Biosci. Biotech. Biochem. 57(3): 444-449. (1993).

Nakagawa T, Maeshima M, Nakamura K, Asahi T. The nuclear gene for subunit Vc of sweet potato cytochrome c oxidase. Plant Cell Physiol Jun;34(4):621-626 （1993）

Stevan Marcus, Michael Wigler, Hao-Peng Xu, Roymarie Ballestar, Makoto Kawamukai and Anthony Polverino. RAS function and protein kinase cascades. p53-66. In 'The GTPase superfamily' John Wiley & Son Press. (1993).

Ryutaro Utsumi, Shie Kusafuka, Takahiro Nakayama, Kan Tanaka, Yuko Takayanagi, 　　Hideo Takahashi, Manjiro Noda and Makoto Kawamukai. Stationary phase- 　　specific expression of fic gene in Escherichia coli K-12 is controlled by the rpoS gene product (σ３８). FEMS Microbiol. Lett. 113:273-278. (1993).

Makoto Kawamukai, Jeffrey Gerst, Jeffrey Field, Michael Riggs, Linda Rodgers, Michael Wigler and Dallan Young. Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombe. Mol. Biol. Cell 3:167-180. (1992).

Tsuyoshi Nakagawa, Ken-ichi Katashiba, Makoto Kawamukai, Hideo Ochiai and Hideyuki Matsuda. Import of the nuclear-coded cytochrome C oxidase subunit into plant mitochondria. In Research in photosynthesis vol III (Norio Murata ed.) 157-160. (1992).

Yukikazu Yamasaki, Ikuo Fukoumoto, Naoki Kumagai, Yukari Ohta, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Continuous chitosan hydrolyzate production by immobilized chitosanolytic enzyme from Enterobacter sp. G-1. Biosci. Biotech. Biochem. 56 (10): 1546-1551. (1992).

Yukikazu Yamasaki, Yukari Ohta, Kenji Morita, Tsuyoshi Nakagawa, Makoto Kawamukai and Hideyuki Matsuda. Isolation, identification, and effect of oxygen supply on cultivation of chitin and chitosn degrading bacterium. Biosci. Biotech. Biochem. 56 (8): 1325-1326. (1992).

Tohru Komano, Ryutaro Utsumi and Makoto Kawamukai, Functional analysis of the fic gene involved in regulation of cell division. Res Microbiol., 142:269-277 (1991).

Makoto Kawamukai, Ryutaro Utsumi, Kazuhiko Takeda, Akihisa Higashi, Hideyuki Matsuda, Yong-Lark Choi and Tohru Komano, Nucleotide sequence and characterization of the sfs1 gene:sfs1 is involved in CRP*-dependent mal gene expression in Escherichia coli. J. Bacteriol., 173:2644-2648. (1991).

Makoto Kawamukai, Kenn Ferguson, Mike Wigler and Dallan Young, Genetics and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe., Mol. Biol. Cell（Cell Regulation）, 2:155-164. (1991).